Royal Air Force Typhoon FGR4s have operated alongside French aircraft in a joint strike targeting an subterranean weapons facility in Syria used by the Daesh militant organization, according to the UK's MoD.
The site, pinpointed through intelligence, was thought to be containing munitions and bombs, the statement said, and was situated in mountainous terrain just north of the ancient city of Palmyra in Syria's central region.
"The RAF jets used Paveway IV guided bombs to hit a series of access tunnels providing entry to the facility... early reports are that the target was engaged successfully," the MoD said.
There was no indication of any harm to civilians in the attack late on Saturday and each participating jet made a safe return, the defence officials confirmed.
The Typhoon fighters were backed up by a Voyager tanker plane.
IS - also known as the so-called Islamic State - enforced jihadist rule over parts of Syria and Iraq until 2019.
"This operation shows our UK leadership, and determination to operate in unison with our allies, to stamp out any resurgence of Daesh and their harmful and extremist ideologies in the region," the British Defence Secretary John Healey said.
RAF aircraft have carried out surveillance missions over Syrian airspace to "prevent any attempted comeback" of IS following its defeat at the Baghuz confrontation in the year 2019, the MoD reported.
"I extend gratitude to all the members of the UK armed forces involved in this mission for their skill and their courage," he added. "Including them were a great many UK service members on duty over Christmas and New Year. This action, to remove dangerous terrorists who threaten our security, shows how UK forces are ready to step up, all year round, keeping Britain secure within its borders and strong abroad."
Last December, the American forces conducted what it termed a "massive strike" on IS targets in the country, subsequent to an ambush killed two US troops and a local interpreter in the Palmyra area.
The U.N. estimates Islamic State still boasts between 5,000 and 7,000 fighters in Iraq and Syria.
